Does Your Body Really Need This Supplement?
Cut through marketing hype. We rigorously separate formulations with proven clinical benefit from those that irritate your gut or conflict with your prescriptions using 14,786 peer-reviewed PubMed trials.
“Why Did a Popular Supplement
Upset Your Stomach?”
Bloating from calcium often comes from Calcium Carbonate; diarrhea from magnesium comes from Magnesium Oxide. Match the exact chemical salt or chelate form to your GI tolerance and current prescriptions.
Personal Body-Fit & Rx Filter
Select your GI traits or active prescription medications. Every monograph below will immediately display personalized compatibility and contraindication alerts.
Complete 591-Supplement Monograph Archive
Showing 24 of 591 matching supplements (Total 591)
Vitamin B3 (Niacinamide)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 75 PubMed studies): Updated Meta-Analysis on Vitamin Supplementation for Chronic Pruritus: Expanding Evidence Beyond Vitamin D.
Vitamin B9 (Folate)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 75 PubMed studies): Spina bifida in Africa: A systematic review and Meta-Analysis of Presentation, Management, and outcomes.
Vitamin B9 (Folic Acid)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 75 PubMed studies): Spina bifida in Africa: A systematic review and Meta-Analysis of Presentation, Management, and outcomes.
Vitamin B1 (Thiamine)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 64 PubMed studies): Evaluation of synergistic antimicrobial effect of vitamins (A, B1, B2, B6, B12, C, D, E and K) with antibiotics against resistant bacterial strains.
Vitamin B2 (Riboflavin)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 64 PubMed studies): Vitamin B2 (riboflavin) and a mixture of vitamin B2 and C affects MMC efficiency in aerated media under irradiation.
Vitamin B12 (Cobalamin)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 63 PubMed studies): Association between vitamin B12 deficiency and long-term use of acid-lowering agents: a systematic review and meta-analysis.
Vitamin C (Ascorbic Acid)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 62 PubMed studies): Therapeutic Role of HAT Therapy in Sepsis: A Systematic Review and Meta-Analysis.
Vitamin A (Retinol)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 55 PubMed studies): Association between vitamin A, retinol intake and blood retinol level and gastric cancer risk: A meta-analysis.
Vitamin B6 (Pyridoxine)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 53 PubMed studies): Chemical and in vivo studies of interaction between cadmium and vitamin B6.
Vitamin B5 (Pantothenic Acid)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 51 PubMed studies): Revealing VNN1: An Emerging and Promising Target for Inflammation and Redox Balance.
Green Tea Extract (EGCG)
BOTANICALS · Evidence Monograph
Clinical evidence (HIGH GRADE, 51 PubMed studies): Green Tea and Epigallocatechin Gallate (EGCG) for Cancer Prevention: A Systematic Review and Meta-Analysis.
Vitamin B3 (Niacin)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 49 PubMed studies): The Role of Nicotinamide as Chemo-Preventive Agent in NMSCs: A Systematic Review and Meta-Analysis.
Vitamin B7 (Biotin)
VITAMINS · Evidence Monograph
Clinical evidence (HIGH GRADE, 47 PubMed studies): Vitamin supplementation in the treatment of optic neuritis: A systematic review and meta-analysis.
Zinc (Picolinate)
MINERALS · Evidence Monograph
Clinical evidence (HIGH GRADE, 45 PubMed studies): Quantifying production responses to the supplementation of chromium in lactating dairy cattle.
L-Cysteine
AMINO ACIDS · Evidence Monograph
Clinical evidence (HIGH GRADE, 45 PubMed studies): Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates.
Collagen Peptides (Skin)
DERMATOLOGY · Evidence Monograph
Clinical evidence (HIGH GRADE, 45 PubMed studies): Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.
Keratin (Hair)
DERMATOLOGY · Evidence Monograph
Clinical evidence (HIGH GRADE, 45 PubMed studies): Efficacy of polyphenolic compounds for hair regeneration: a systematic review and meta-analysis of randomized controlled trials.
MSM (Skin/Hair)
DERMATOLOGY · Evidence Monograph
Clinical evidence (MODERATE GRADE, 45 PubMed studies): Recent advances in bioactive coumarin scoparone: A comprehensive review.
Tart Cherry Extract
BOTANICALS · Evidence Monograph
Clinical evidence (MODERATE GRADE, 44 PubMed studies): Effects of Tart Cherry Extract Supplementation on Plasma Urate and C-Reactive Protein Levels in Healthy Adults: a Randomized Controlled Trial.
Forsythia suspensa
TRADITIONAL · Evidence Monograph
Clinical evidence (MODERATE GRADE, 43 PubMed studies): Integrative network pharmacology and experimental validation of multi-target synergy against multidrug-resistant klebsiella pneumoniae via PI3K/AKT-MAPK pathway disruption.
Organ Meat Complex
MONOGRAPH · Evidence Monograph
Clinical evidence (MODERATE GRADE, 43 PubMed studies): Monitoring water contamination through shellfish: A systematic review of biomarkers, species selection, and host response.
Selenium (Selenomethionine)
MINERALS · Evidence Monograph
Clinical evidence (HIGH GRADE, 42 PubMed studies): Clinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis.
Soil-based Probiotic
PROBIOTICS · Evidence Monograph
Clinical evidence (HIGH GRADE, 42 PubMed studies): Isolation and Characterization of Putative Probiotic Bacterial Strain, Bacillus amyloliquefaciens, from North East Himalayan Soil Based on In Vitro and In Vivo Functional Properties.
Siberian Ginseng (Eleutherococcus)
BOTANICALS · Evidence Monograph
Clinical evidence (MODERATE GRADE, 42 PubMed studies): Eleutheroside K isolated from Acanthopanax henryi (Oliv.) Harms suppresses methicillin resistance of Staphylococcus aureus.
Six Clinical Formulation & Drug-Interaction Protocols Before You Supplement
Dive into peer-reviewed formulation science—chelate vs. inorganic salt bioavailability, prescription drug contraindications, chronobiology dosing windows, alopecia protocols, and Omega-3 purity.
Chelate vs. Inorganic Salt Bioavailability & GI Tolerability
Identical elemental labels hide vast pharmacokinetic differences. Compare inorganic salts (Magnesium Oxide, Calcium Carbonate) against amino-acid chelates (Bisglycinate, Citrate) for bioavailability and GI comfort.
Read Formulation Guide →Prescription Drug–Supplement Interaction & Contraindication Matrix
Audit 122 documented pharmacokinetic and pharmacodynamic drug-supplement interactions—covering anticoagulants, levothyroxine chelation, metformin B12 depletion, and serotonergic toxicity.
Read Formulation Guide →Chronobiology Dosing Schedule: Morning Fasted vs. Evening Post-Meal
Taking B-complex or CoQ10 at night can disrupt sleep architecture, while taking fat-soluble Vitamin D, Omega-3, or CoQ10 on an empty stomach slashes micellar absorption. Optimize your daily timing.
Read Formulation Guide →Alopecia Protocol: Androgenetic DHT vs. Diffuse Ferritin & Keratin
Androgenetic miniaturization (DHT-driven) and diffuse telogen effluvium (ferritin/amino-acid depletion) require distinct interventions. Review RCT evidence for Pumpkin Seed Oil, Medicinal Yeast, and Biotin safety.
Read Formulation Guide →Omega-3 Monograph: rTG vs. EE Bioavailability, Oxidation & Dose Thresholds
Evaluate Omega-3 formulations across chemical backbone (rTG vs. Ethyl Ester), EPA:DHA ratios, TOTOX oxidation limits, and clinical dose thresholds for hypertriglyceridemia vs. dry eye.
Read Formulation Guide →NICEVIVA GRADE Evidence Methodology & 14,357-Study PubMed Audit
Zero ads or sponsorships. Explore how NICEVIVA synthesizes 14,786 PubMed clinical studies across 591 supplements using GRADE criteria, sample sizes, and 95% confidence intervals.
Read Formulation Guide →